Depression Home > Venlafaxine XR Dosing

For people with depression, social anxiety disorder, or generalized anxiety disorder, venlafaxine XR dosing typically starts at 75 mg daily. The usual starting dose of venlafaxine XR for the treatment of panic disorder is 37.5 mg daily. Besides the medical condition being treated, a few other factors that can affect venlafaxine XR dosing include your age, other medical conditions you may have, and other drugs you may be currently taking. You should be sure to take the venlafaxine XR capsules with food, and should avoid breaking, chewing, or crushing them.

Venlafaxine XR Dosing: An Introduction

The dose of venlafaxine XR (Effexor XR®) that your healthcare provider prescribes will vary depending on a number of factors, including:
  • Your age
  • The medical condition being treated
  • Other medical conditions you may have
  • Other medications you may be taking.
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
Venlafaxine XR is usually taken once daily. In contrast, regular venlafaxine is taken two or three times a day.
Venlafaxine XR Dosing for Depression, Social Anxiety, and Generalized Anxiety
For the treatment of depression, social anxiety disorder, or generalized anxiety disorder, the usual starting dosage of venlafaxine XR is venlafaxine XR 75 mg each day. Your healthcare provider may increase your dose to venlafaxine XR 150 mg daily after four to seven days if you tolerate venlafaxine XR well. Some people may be started at venlafaxine XR 37.5 mg each day and increased to 75 mg within four to seven days before being increased to 150 mg daily. Your healthcare provider may increase your dose up to venlafaxine XR 225 mg once daily if needed to treat depression.
It should be noted that only Effexor XR capsules (not generic venlafaxine XR tablets) are approved for treating generalized anxiety disorder.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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