If you have major depression, your healthcare provider may recommend a medication called Viibryd. This drug comes in the form of a tablet and is generally taken once a day, preferably at the same time each day. Diarrhea, nausea, and insomnia are some of the most commonly reported side effects of this medicine. However, in most cases, it is well tolerated.
Viibryd is distributed by Forest Pharmaceuticals, Inc.
How Does Viibryd Work?
The exact way that Viibryd works to treat depression is unknown. Viibryd works on a specific brain chemical called serotonin. Serotonin is one of several chemicals used to send messages between nerves. When levels become unbalanced, it can cause a variety of conditions, including depression.
Viibryd increases the activity of serotonin in the brain by blocking the reuptake of serotonin by nerves, allowing more to be available in the space between the nerves. It also acts as a partial agonist at certain serotonin receptors. This means it binds to the receptors, but only causes part of the response that would be expected from the binding of serotonin itself.
Clinical Effects of Viibryd
Clinical studies have shown that this medication can improve symptoms of depression in people with major depressive disorder. In these studies, people taking Viibryd had a greater improvement in depressive symptoms than people taking a placebo (a "sugar pill" with no active ingredients) over eight weeks.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Viibryd [package insert]. St. Louis, MO: Forest Laboratories, Inc.;2012 December.
Viibryd Medication Guide. New Haven, CT: Trovis Pharmaceuticals LLC.;2010 January.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed March 11, 2011.
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