Depression Home > Wellbutrin for Depression

Wellbutrin® (bupropion hydrochloride) is a prescription medication approved to treat depression (also known as major depression or clinical depression).
Wellbutrin is part of a group of medications called norepinephrine and dopamine reuptake inhibitors, or NDRIs for short. NDRIs affect specific chemicals within the brain, known as norepinephrine and dopamine. When the levels of dopamine and norepinephrine become unbalanced, it can cause a variety of conditions, including depression. Wellbutrin helps block the reuptake of norepinephrine and dopamine so that more remains in the space between the brain's nerve cells.
Although most people tolerate this medication well, it is not suitable for everyone. Before starting treatment with Wellbutrin, make sure to talk to your healthcare provider about any other medical conditions you may have or any other medications you are taking (including vitamins and herbal supplements). For instance, you may not be able to safely take Wellbutrin if you have conditions such as diabetes, liver disease, or epilepsy. Some of the common side effects of Wellbutrin include headaches, nausea, and dizziness.
(Click Wellbutrin for a more in-depth look at using Wellbutrin for depression treatment. This article also discusses how Wellbutrin works and offers information on general precautions, dosages, and potential side effects.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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