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Zoloft and Burning Sensation: An Overview

A burning sensation is an infrequent side effect of Zoloft® (sertraline hydrochloride). The medical term for this burning sensation is paresthesia. People taking Zoloft may feel this burning or prickling sensation in the hands, arms, legs, or feet, but it can also occur in other parts of the body. The sensation, which normally occurs without warning, is usually painless and described as tingling or numbness, skin crawling, or itching.

How Common Is a Burning Sensation With Zoloft?

Based on previous clinical studies, a burning sensation occurred in 2 percent of people taking Zoloft. If you experience a burning sensation while taking Zoloft, talk with your healthcare provider. It is possible that if the burning sensation is bothersome to you, your doctor may recommend adjusting the Zoloft dosage or trying another medicine for your condition.
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Last reviewed by: Kristi Monson, PharmD;
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