Depression Home > Zoloft Dosage

The Zoloft dosage that doctors usually recommend for adults with depression or obsessive-compulsive disorder is 50 mg once a day. Although the starting dose for people with panic disorder, post-traumatic stress disorder, or social anxiety disorder is typically 25 mg daily, healthcare providers often increase that dose to 50 mg daily. The recommended dosage of Zoloft for children with OCD is usually 25 mg daily.

An Overview of Zoloft Dosage

The dose of Zoloft® (sertraline hydrochloride) your healthcare provider prescribes will vary, depending on a number of factors, including:
 
  • Your age
  • The medical condition for which you are being treated
  • Other medical conditions you may have
  • Other medications you may be taking.
     
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 

Dosage of Zoloft for Depression or Obsessive-Compulsive Disorder

The recommended starting Zoloft dose for people with depression or obsessive-compulsive disorder (OCD) is Zoloft 50 mg once a day. Your healthcare provider may choose to increase the dosage if symptoms continue, or decrease it if side effects occur.
 

Zoloft Dose for Panic Disorder, Post-Traumatic Stress Disorder, or Social Anxiety Disorder

The recommended starting dose of Zoloft for people with panic disorder, post-traumatic stress disorder (PTSD), or social anxiety disorder is Zoloft 25 mg once a day. After a week, your healthcare provider will likely increase the dose to 50 mg of Zoloft once a day. He or she may also choose to increase the Zoloft dosage if symptoms continue, or decrease the dose if side effects occur.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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