Nortriptyline hydrochloride (
Pamelor®) is a prescription medicine commonly used for the treatment of
depression. It belongs to a class of
antidepressants known as
tricyclic antidepressants, which work by affecting levels of certain brain chemicals (including serotonin and norepinephrine).
Several clinical studies have been conducted on the effects of nortriptyline. Studies have shown the drug to be effective for
depression treatment. It may also be used "
off-label" to help relieve chronic pain and to prevent
migraine headaches; other off-label uses include
bedwetting, attention deficit hyperactivity disorder (
ADHD),
fibromyalgia, and
bulimia. The medicine is also effective at helping people quit smoking.
It is important to note that it may take a few weeks before significant changes in mood occur.
(Click Nortriptyline to learn more about nortriptyline's effects, information on how this drug works, general dosing guidelines, and more.)