People who have
depression (also called clinical depression or major depression) may benefit by taking
nortriptyline hydrochloride (
Pamelor®). This
tricyclic antidepressant affects the levels of serotonin and norepinephrine in the brain, allowing more to remain, which may be how it works to relieve depression symptoms.
In adults, the usual starting dose is 25 mg, taken either three times a day, for a total of 75 mg of nortriptyline, or four times a day, for a daily total of 100 mg. In general, no more than 100 mg of nortriptyline should be taken in a 24-hour period. If your healthcare provider thinks you should take more than this, the level of medication in your blood should be monitored.
(Click Nortriptyline Dosing for an explanation of the factors that affect the exact amount a person is prescribed, patient groups that should take a lower dose, and how to ensure your safety and the drug's effectiveness during treatment.)