Medications
 
 

Nortriptyline for Depression

People who have
 depression (also called major depression or clinical depression) often take nortriptyline hydrochloride (Pamelor®) to relieve symptoms. The medication is thought to work by affecting the levels of certain chemicals in the brain -- namely norepinephrine and serotonin -- allowing more to remain. It is taken anywhere from one to four times a day. Common side effects include dizziness, drowsiness, constipation, and dry mouth.
 
When taking nortriptyline for depression, it is important to remember that it can take several weeks for the medication to reach its full effectiveness, so do not be discouraged if it doesn't appear to be working at first. Do not stop taking nortriptyline or adjust your dosage without talking to your healthcare provider.
 
(To learn more about taking this medication for depression, click Nortriptyline. This article describes general dosing guidelines, lists other possible side effects, and addresses what to discuss with your healthcare provider before beginning treatment.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD