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Olanzapine and Fluoxetine Side Effects

Serious Olanzapine and Fluoxetine Side Effects

Some side effects with olanzapine and fluoxetine, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
 
 
 
  • Large or rapid weight gain
 
  • Suicidal thoughts or behavior
 
  • Dizziness or fainting when going from a sitting or lying-down position to standing
 
  • Feelings of restlessness or jitteriness
 
  • Any abnormal muscle movements (these abnormal movements can become permanent if the medication is not stopped quickly)
 
  • Signs or symptoms of neuroleptic malignant syndrome (NMS), which can include:
 
    • A high fever
    • Stiff muscles
    • Confusion
    • An irregular pulse or blood pressure
    • An increased heart rate (tachycardia)
    • Sweating
    • An irregular heart rhythm (arrhythmia)
 
  • Signs of an allergic reaction, including:
 
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling
    • Wheezing
    • Difficulty breathing or swallowing.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
 
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