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What Is Olanzapine and Fluoxetine Used For?

Olanzapine and Fluoxetine for Treatment-Resistant Depression

For many people, simply taking an antidepressant can adequately treat depression. However, sometimes depression can be difficult to treat. You may have tried several different antidepressants (or even combinations of antidepressants) without experiencing adequate relief from your symptoms. This is known as treatment-resistant depression.
 
Olanzapine and fluoxetine is approved for treatment-resistant depression in people that have not responded to two different antidepressants (at adequate doses and for an adequate length of time) during the current depression episode.
  

Is Olanzapine and Fluoxetine Used for Children?

Olanzapine and fluoxetine has not been approved for treating bipolar disorder in children. Be sure to talk with your healthcare provider about the risks and benefits of using the medication in children.
 

Is Olanzapine and Fluoxetine Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend olanzapine and fluoxetine for something other than the condition discussed in this article. This is called an "off-label" use. At this time, olanzapine and fluoxetine is sometimes used in an off-label fashion to treat depression that is not associated with bipolar disorder.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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