How Does Oleptro Work?It is not entirely clear how Oleptro works. There are no other medications that work exactly like it (other than the short-acting version of trazodone). Oleptro acts on a specific chemical within the brain known as serotonin. Serotonin is one of several chemicals used to send messages in between the nerves; but, when serotonin levels become unbalanced, it can cause a variety of conditions, including depression.
Oleptro helps to block the reuptake of serotonin (so that more serotonin is available for the nerves in the brain), which returns the serotonin back to its "normal" levels. However, unlike selective serotonin reuptake inhibitors (SSRIs), trazodone may also block certain serotonin receptors.
Can Children Use It?Oleptro is not approved for children (usually defined as individuals under the age of 18 years old). It is not known if this medication is safe or effective for children.
Off-Label Uses for OleptroOn occasion, your healthcare provider may recommend Oleptro for something other than depression (this would be known as an "off-label" use). Based on off-label uses of short-acting trazodone (Desyrel®), possible off-label uses of Oleptro might include the treatment of the following conditions:
It is possible that the extended-release properties of Oleptro might not make it a good choice for some of these off-label uses (for instance, taking this medication for insomnia might lead to excessive daytime drowsiness).