Medications
 
 

Pamelor Drug Interactions

Pamelor Interactions Explained

The following sections explain in detail the interactions that can occur when Pamelor is combined with any of the drugs listed above.
 
Alcohol
Pamelor may enhance the effects of alcohol. This can lead to an increased risk for suicidal thoughts and other Pamelor overdose symptoms. Make sure to talk with your healthcare provider about drinking alcohol while taking Pamelor.
 
Anticholinergic Medications
Taking Pamelor with anticholinergic medications may cause increased side effects. Talk to your healthcare provider before using these medications together, as your dosages may need to be reduced. Since some of these types of medicines are found in over-the-counter medicines, do not treat yourself for the common cold, a cough, or allergies without first talking to your healthcare provider.
 
Arrhythmia Medications
Taking Pamelor with arrhythmia medications can increase your risk of a dangerous arrhythmia called QT prolongation. Also, certain arrhythmia medications can increase the level of Pamelor in your blood, increasing your risk of side effects. Talk to your healthcare provider before taking these medications together.
 
Barbiturates
Taking Pamelor with barbiturates can increase the risk of side effects of both Pamelor and barbiturates, such as drowsiness or dizziness. Your healthcare provider may need to adjust your dose of these medications.
 
Chlorpropamide (Diabinese)
There has been one report of a person experiencing low blood sugar (hypoglycemia) after taking chlorpropamide and Pamelor together. Your healthcare provider may need to monitor your blood sugar more closely, especially when starting or stopping Pamelor.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
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