Parnate and Pregnancy: An Overview
For women who are pregnant,
Parnate® (
tranylcypromine sulfate) may not be safe. Parnate is used to treat
depression and is part of a group of medications called monoamine oxidase inhibitors (MAOIs).
Parnate and Pregnancy Risk
The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. However, the FDA has not given Parnate a pregnancy risk classification, as is common with older medications. There is very little information available about the use of Parnate during pregnancy.
There have been a few reports of birth defects and stillbirths in women taking Parnate, but it is not known if these problems were actually caused by the medicine itself. It is not known how Parnate might affect a growing fetus. However, since MAOIs (like Parnate) are usually used as a last resort in people with severe depression, it may not be possible for some pregnant women to stop taking Parnate. In fact, depression in the mother can be damaging to the baby.
Recommendations for Using Parnate During Pregnancy
If you are pregnant or thinking about becoming pregnant, let your healthcare provider know. He or she will consider both the benefits and risks of Parnate during pregnancy before making a recommendation for your particular situation.
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