Parnate and Pregnancy
There have been a few reports of birth defects in babies born to women taking Parnate during pregnancy. However, it is not known whether these problems were actually caused by the drug itself. If you are taking Parnate and pregnancy occurs, be sure to talk to your healthcare provider right away.
For women who are pregnant, Parnate® (tranylcypromine sulfate) may not be safe. Parnate is used to treat depression and is part of a group of medications called monoamine oxidase inhibitors (MAOIs).
The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. However, the FDA has not given Parnate a pregnancy risk classification, as is common with older medications. There is very little information available about the use of Parnate during pregnancy.
There have been a few reports of birth defects and stillbirths in women taking Parnate, but it is not known if these problems were actually caused by the medicine itself. It is not known how Parnate might affect a growing fetus. However, since MAOIs (like Parnate) are usually used as a last resort in people with severe depression, it may not be possible for some pregnant women to stop taking Parnate. In fact, depression in the mother can be damaging to the baby.
If you are pregnant or thinking about becoming pregnant, let your healthcare provider know. He or she will consider both the benefits and risks of Parnate during pregnancy before making a recommendation for your particular situation.