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Pristiq Side Effects

Pristiq Side Effects to Report

Some side effects with Pristiq, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
 
  • Suicidal thoughts or behavior (see Depression and Suicide)
  • Anxiety, agitation, or panic attacks
  • Hostility or aggressiveness
  • Engaging in unusual or dangerous activities
  • Restlessness or inability to sit still
  • Extreme elation or feeling of happiness that may switch back and forth with a depressed or sad mood
  • Other unusual changes in behavior
  • Signs of serotonin syndrome (a rare but dangerous problem associated with certain medications), such as:
    •  
    • Confusion or other mental changes
    • A rapid heart rate
    • Nausea, vomiting, or diarrhea
    • Hallucinations
    • Blood pressure changes
    • An irregular heart rhythm
    • Overactive reflexes
    • Fever, sweating, or shivering
    • Shakiness
    • Agitation
    • Seizures
    • Coma
 
  • Feelings of a rapidly or forcefully beating heart (known as heart palpitations)
  • Seizures
  • A high fever
  • High blood pressure (hypertension)
  • Easy bruising or bleeding
  • Low sodium levels in the blood (hyponatremia)
  • Signs of an allergic reaction, such as:
 
    • Unexplained rash
    • Hives
    • Itching
    • Unexplained swelling
    • Wheezing
    • Difficulty breathing or swallowing.
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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