Protriptyline can potentially interact with a number of medications (see Drug Interactions With Protriptyline).
You should talk with your healthcare provider prior to taking protriptyline if you have:
- Bipolar disorder or a family history of bipolar disorder (also known as manic depression)
- A history of suicide attempts or suicidal thoughts
- Severe anxiety or agitation
- A recent history of heart attack
- Heart problems, including heart disease
- Hyperthyroidism (overactive thyroid)
- Seizures or epilepsy
- Bladder problems or difficulty passing urine
- An enlarged prostate (also known as benign prostatic hyperplasia or BPH)
- Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you:
- Are pregnant or thinking of becoming pregnant (see Vivactil and Pregnancy)
- Are breastfeeding (see Vivactil and Breastfeeding)
- Drink alcohol regularly.
Be sure to tell your healthcare provider about all other medicines you may be taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Protriptyline to learn more, including information on who should not take the drug.)