Prozac and Sex Drive

As with all selective serotonin reuptake inhibitors (SSRIs), Prozac® (fluoxetine hydrochloride) can cause sexual side effects, such as impotence, priapism, ejaculation problems, and a decreased sex drive. Prozac was shown to cause a decreased sex drive in up to 11 percent of people taking the medication during clinical studies. These studies also showed that up to 7 percent of men taking Prozac may experience ejaculation problems or impotence.
It is impossible for your healthcare provider to know whether or not you will develop any of these sexual side effects. Also, if a person does develop what appear to be sexual side effects of the medication, it is often difficult to know whether these problems are the result of Prozac or other factors. For example, one-third of people with untreated depression report sexual side effects.
If you notice a change in your sex drive while taking Prozac, make sure to talk with your healthcare provider. There is treatment that he or she may be able to recommend. Depending on the severity of your side effects, your healthcare provider may recommend that you adjust your dosage or try another depression medicine.
(Click Prozac Sexual Side Effects for a more in-depth look at Prozac and sex drive, including information on how this medication can cause sexual side effects, such as impotence, ejaculation problems, and a decreased sex drive.)
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