Insomnia, weakness, and loss of appetite are among the most common side effects reported with Prozac. Side effects that are rare (seen in less than 1 percent of patients) include canker sores, high cholesterol, and acne. In most cases, Prozac side effects are minor and either do not require medical attention or can be treated easily. However, if you develop any serious problems, such as suicidal thoughts or behavior, hallucinations, or panic attacks, notify your healthcare provider immediately.

• Insomnia -- in up to 33 of people (see Prozac and Insomnia)
• Nausea -- up to 29 percent
• Weakness -- up to 21 percent
• Headache -- up to 21 percent
• Diarrhea -- up to 18 percent
• Loss of appetite -- up to 17 percent (see Prozac and Weight Loss)
• Drowsiness -- up to 17 percent
• Anxiety -- up to 15 percent
• Nervousness -- up to 14 percent
• Shakiness (tremor) -- up to 13 percent
• Dry mouth -- up to 12 percent (see Prozac and Dry Mouth)
• Decreased sex drive -- up to 11 percent (see Prozac Sexual Side Effects)
• Yawning -- up to 11 percent
• Indigestion -- up to 10 percent
• Dizziness -- up to 9 percent
• Sweating -- up to 8 percent
• Impotence -- up to 7 percent (see Prozac Sexual Side Effects)
• Ejaculation problems -- up to 7 percent (see Fluoxetine and Premature Ejaculation).
   

• Flushing (redness of the skin, especially the face)
• Abnormal dreams
• Constipation
• Gas
• Vomiting
• Fever or chills
• Weight loss (see Prozac and Weight Loss)
• Vision changes
• Chest pain
• High blood pressure (hypertension)
• Increased appetite and weight gain (see Prozac and Weight Gain)
• Taste changes.