Remeron Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
Remeron is combined with any of the drugs listed above.
Alcohol
It is not recommended that people drink alcohol while taking Remeron. Combining the two may cause unwanted side effects (see
Remeron and Alcohol).
Benzodiazepines
Remeron and benzodiazepines both cause drowsiness, and taking them together increases your chance of drowsiness and other side effects. Talk to your healthcare provider before taking these medications together.
CYP 3A4 Inducers
The liver metabolizes (breaks down) Remeron using certain enzymes known as CYP 3A4 enzymes. Certain other drugs are known to speed up the activity of CYP 3A4; such drugs are known as CYP 3A4 inducers. These medications may increase the breakdown of Remeron, leading to low levels of Remeron in the blood, and perhaps decreased effectiveness of the medication. Check with your healthcare provider before combining such medications.
CYP 3A4 Inhibitors
The liver metabolizes (breaks down) Remeron using certain enzymes known as CYP 3A4 enzymes. Certain other drugs are known to lower the activity of CYP 3A4; such drugs are known as CYP 3A4 inhibitors. These medications may slow the breakdown of Remeron, leading to high levels of Remeron in the blood, and perhaps an increased risk of side effects. Check with your healthcare provider before combining such medications.
Linezolid
Taking Remeron with
linezolid can increase the risk of a group of symptoms called serotonin syndrome. These symptoms include:
- Confusion
- Hallucination
- Fast heartbeat
- Feeling faint
- Fever
- Sweating
- Muscle spasm
- Difficulty walking
- Diarrhea.
Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any of these symptoms, as serotonin syndrome can be dangerous.