Sinequan Warnings and Precautions

Some Precautions and Warnings With Sinequan

Some Sinequan precautions and warnings to be aware of include:
  • Antidepressants (including Sinequan) may increase the risk of suicidal thinking or behavior in children, teenagers, and adults (see Depression and Suicide for more information). Therefore, if you notice any changes in symptoms or new symptoms, talk to your healthcare provider immediately. Some of these symptoms may include: anxiety, hostility, agitation, panic, restlessness, hallucinations, extreme hyperactivity, and suicidal thinking or behavior (see Doxepin and Suicide for more information).
  • Before prescribing Sinequan for depression, your healthcare provider should make sure that you do not have bipolar disorder (instead of depression). Sometimes, the symptoms of bipolar disorder and depression are very similar, and Sinequan can cause problems in people with bipolar disorder.
  • For people taking Sinequan, caution should be used when driving, operating heavy machinery, or performing other tasks that require concentration, especially when first starting Sinequan or when switching dosages. This is because Sinequan may affect a person's mental or physical ability to perform these tasks. Make sure to understand how Sinequan affects you before performing any tasks that require mental or physical concentration.
  • Sinequan can interact with certain medications (see Sinequan Drug Interactions).
  • Sinequan may enhance the effects of alcohol and medicines that affect the brain. This can lead to an increased risk for drowsiness, dizziness, suicidal thoughts, and other Sinequan overdose symptoms. Make sure to talk with your healthcare provider about drinking alcohol while taking Sinequan.
  • Sinequan may not be safe for use during pregnancy. Discuss the benefits and risk of using Sinequan during pregnancy with your healthcare provider (see Doxepin and Pregnancy for more information).
  • Sinequan passes through breast milk and may cause harm to your nursing baby. Therefore, if you are breastfeeding or plan to start breastfeeding, be sure to talk with your healthcare provider about what makes the most sense for your particular situation (see Doxepin and Breastfeeding).
  • Special care should be used when taking Sinequan if you have a history of seizures, as tricyclic antidepressants (such as Sinequan) can make seizure disorders worse.
  • Sinequan may cause a dry mouth. Sucking on hard candy, chewing gum, or melting bits of ice in your mouth can provide relief.
  • The elderly appear to be more sensitive to Sinequan, which can increase their risk of side effects (such as delirium and confusion). In these particular situations, healthcare providers will start people with lower doses of Sinequan and monitor them more closely.
  • Do not treat yourself for the common cold, a cough, or allergies without first talking to your healthcare provider. Some over-the-counter medicines used to treat these conditions can increase the risk for developing Sinequan side effects.
  • Do not stop taking Sinequan without first discussing it with your healthcare provider. Stopping the medicine abruptly may increase the risk for withdrawal symptoms (see Sinequan Withdrawal).
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