SSRIs and Pregnancy

SSRIs and Pregnancy: Third Trimester Concerns

There have been reports where fetuses being exposed to SSRIs during the third trimester of pregnancy develop complications that require hospitalization, respiratory support, and/or tube feeding. These newborns experienced a number of symptoms, including:
  • Difficulty breathing
  • Seizures
  • Lack of oxygen in the blood
  • Feeding difficulties
  • Tremors
  • Irritability
  • Constant crying.
Also, babies who are exposed to SSRIs during late pregnancy are also at an increased risk for developing persistent pulmonary hypertension of the newborn (PPHN). PPHN is associated with significant complications and even death. Women who take an SSRI after week 20 of pregnancy are six times more likely to deliver a baby with PPHN.

Recommendations for Using SSRIs During Pregnancy

If you are pregnant or thinking about becoming pregnant, let your healthcare provider know. Your healthcare provider will consider both the benefits and the risks of taking SSRIs during pregnancy before making a recommendation for your particular situation.
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