SSRIs (selective serotonin reuptake inhibitors) affect a specific chemical within the brain known as serotonin. Serotonin is one of several chemicals used to send messages from one nerve cell to another.
As a message travels down a nerve, it causes the end of the cell to release serotonin. The serotonin enters the gap between the first nerve cell and the one next to it. When enough serotonin reaches the second nerve cell, it activates receptors on the cell and the message continues on its way. The first cell then quickly absorbs any serotonin that remains in the gap between the cells. This is called "reuptake."
Normally, this process works without any problems. But when the levels of serotonin become unbalanced, it can cause a variety of conditions, including
depression. SSRI
antidepressants help to block the reuptake of serotonin so more serotonin remains in the space between the brain's nerve cells. This gives the serotonin a better chance of activating the receptors on the next nerve cell.
SSRIs: When and How Do I Take Them?
Some general considerations for when and how to take SSRI medications include:
- SSRIs are taken by mouth, usually once a day.
- If your SSRI makes you drowsy, try taking it at night. If you experience insomnia due to your SSRI, try taking it in the morning.
- You can take SSRIs with or without food. If your SSRI bothers your stomach, try taking it with food.
- SSRIs should be taken at the same time each day to maintain an even level of the drug in your blood.
- For SSRIs to work properly, they must be taken as prescribed. Your SSRI will not work if you stop taking it.
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