Tofranil Drug Interactions
Tofranil and Serotonin Syndrome
Several of the known interactions with Tofranil are related to a potentially dangerous group of symptoms known as serotonin syndrome. Such symptoms might include:
- Fast heartbeat
- Feeling faint
- Muscle spasm
- Difficulty walking
Tofranil Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when Tofranil is combined with any of the drugs listed above.
Tofranil may enhance the effects of alcohol. This can lead to an increased risk for suicidal thoughts and overdose symptoms. Talk with your healthcare provider about drinking alcohol while taking this medication.
Taking Tofranil with anticholinergic medications may cause increased side effects. Talk to your healthcare provider before using these medications together, as your dosages may need to be reduced. Since anticholinergic medications are found in some over-the-counter medicines, do not treat yourself for the common cold, a cough, or allergies without first talking to your healthcare provider.
Combining Tofranil with arrhythmia medications can increase your risk of a dangerous arrhythmia called QT prolongation. Also, certain arrhythmia medications can increase the level of Tofranil in your blood, which may increase your risk of side effects. Talk to your healthcare provider before taking these medications together.