When and How to Take Tofranil

Considerations for when and how to take the medication include the following:
  • Tofranil comes in tablet form. When used for depression, it is usually taken by mouth one to four times a day. When used for bedwetting, it is usually taken one hour before bedtime.
  • You can take the medication with or without food. If it upsets your stomach, try taking it with food.
  • Tofranil should be taken at the same time(s) each day to maintain an even level in your blood.
  • For the medicine to work properly, you have to take it as prescribed. It will not work if you stop taking it.

Dosing Information

The dose of Tofranil that your healthcare provider recommends will vary, depending on a number of factors, including:
  • Your age
  • The condition being treated
  • Other medical conditions you may have
  • Other medications you may currently be taking.
As with any medication, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
(Click Tofranil Dosage for more information.)

Side Effects

As with any medicine, side effects are possible with Tofranil. However, not everyone who takes the medication will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, they are often minor and either require no treatment or can easily be treated by your healthcare provider. Serious side effects are less common.
Common side effects of tricyclic antidepressants such as Tofranil include:
(Click Tofranil Side Effects to learn more, including some of the more serious side effects that you should report immediately to your healthcare provider.)
You can also read about specific side effects in the following eMedTV articles:
Healthy Pet, Healthy You

Tofranil (Imipramine)

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