More Information on Interactions With Trazodone
The following sections explain in detail the potentially negative interactions that can occur when
trazodone is combined with any of the drugs listed above.
Certain Antibiotics or Antifungals
Taking trazodone with certain antibiotics or antifungals may increase the level of trazodone in your blood, increasing your risk of side effects. Your healthcare provider may need to lower your
trazodone dosage to prevent this from occurring.
Carbamazepine
Carbamazepine can decrease the level of trazodone in your blood, perhaps making trazodone less effective. To preven this, your healthcare provider may need to increase your dose of trazodone.
Delavirdine
Combining trazodone with
delavirdine may increase the level of trazodone in your blood, possibly increasing your risk of side effects. Your healthcare provider may need to lower your trazodone dosage to prevent this interaction from occurring.
Diclofenac
If trazodone and
diclofenac are taken together, this may increase the level of trazodone in your blood, which may increase your risk of side effects. Your healthcare provider may need to lower your trazodone dosage to prevent this.
Digoxin
If digoxin and trazodone are combined, this may increase the level of digoxin in your blood, potentially increasing your risk of side effects. Your healthcare provider may need to monitor the level of digoxin in your blood, especially when starting or stopping trazodone.
Imatinib
Taking trazodone with imatinib may increase the level of trazodone in your blood, potentially increasing your risk of side effects. To prevent this, your healthcare provider may need to lower your trazodone dosage.
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