Trazodone Side Effects

Common Trazodone Side Effects

Trazodone has been studied thoroughly in clinical trials, in which a group of people taking the drug have side effects documented and compared to another group not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
In these studies, the most common side effects of trazodone included:
  • Drowsiness -- in up to 40.8 percent of people
  • Dry mouth -- up to 33.8 percent (see Trazodone and Dry Mouth)
  • Dizziness or lightheadedness -- up to 28 percent
  • Headache -- up to 19.8 percent
  • Nervousness -- up to 14.8 percent
  • Blurred vision -- up to 14.7 percent
  • Nausea or vomiting -- up to 12.7 percent
  • Fatigue -- up to 11.3 percent
  • Constipation -- up to 7.6 percent
  • Low blood pressure (hypotension) -- up to 7 percent
  • Confusion -- up to 5.7 percent
  • Sinus congestion -- up to 5.7 percent
  • Weight loss -- up to 5.7 percent (see Trazodone and Weight Loss)
  • Muscle pain -- up to 5.6 percent
  • Shakiness (tremor) -- up to 5.1 percent.
Other common trazodone side effects (occurring in 1 to 5 percent of people) included:
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