Medications
 
 

Trazodone Substitute

 Trazodone hydrochloride (Desyrel®) is generally quite effective at treating depression. However, alternatives are available if your depression symptoms do not respond to treatment with this medication. You may also wish to try a substitute for trazodone if you develop bothersome side effects.
 
Examples of alternate medications for depression include:
 
Other trazodone substitutes include:
 
  • Therapy
  • Electroconvulsive therapy
  • Alternative (natural) therapies, such as acupuncture, vitamin B6, and omega-3 fatty acids.
     
(To learn more about other substitutes for this antidepressant, click Trazodone Alternatives. This article offers an in-depth list of other depression medications and describes "talk" therapy in more detail.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD