Drug Interactions With Trimipramine

The following sections explain in detail the potentially negative interactions that can occur when trimipramine is combined with any of the drugs listed above.

 

Trimipramine may enhance the effects of alcohol. This can lead to an increased risk of suicidal thoughts and other trimipramine overdose symptoms. Make sure to talk with your healthcare provider about drinking alcohol while taking trimipramine.

 

Taking trimipramine with anticholinergic medications may cause increased side effects. Talk with your healthcare provider before using these medications together, as your dosages may need to be reduced. Since some of these types of medicines are found in over-the-counter medicines, do not treat yourself for the common cold, a cough, or allergies without first talking to your healthcare provider.

 

Taking trimipramine with arrhythmia medications can increase your risk of a dangerous arrhythmia called QT prolongation. Also, certain arrhythmia medications can raise the level of trimipramine in your blood, increasing your risk of side effects. Talk with your healthcare provider before taking these medications together.

 

Taking trimipramine with cimetidine can raise the level of trimipramine in your blood, increasing your chances of side effects. If you are taking trimipramine with cimetidine, your healthcare provider may need to adjust your doses of these medications.

 

Taking trimipramine with MAOIs can increase your chances of developing dangerous side effects. Do not take trimipramine if you have taken an MAOI within the past two weeks.