Precautions and Warnings With Trimipramine
Some trimipramine warnings and precautions to be aware of include:
- Antidepressants (including trimipramine) may increase the risk of suicidal thinking or behavior in children, teenagers, and adults (see Antidepressants and Suicide for more information). Therefore, if you notice any changes in symptoms or new symptoms during treatment with trimipramine, talk with your healthcare provider immediately. Some of these symptoms may include anxiety, hostility, agitation, panic, restlessness, hallucinations, extreme hyperactivity, and suicidal thoughts or behavior (see Surmontil and Suicide for more information).
- Before prescribing trimipramine for depression, your healthcare provider should make sure that you do not have bipolar disorder (instead of depression). Sometimes, the symptoms of bipolar disorder and depression are very similar, and trimipramine can cause problems in people with bipolar disorder.
- Trimipramine may cause a worsening of schizophrenia. Discuss this with your healthcare provider before taking trimipramine.
- People taking trimipramine should use caution when driving, operating heavy machinery, or performing other tasks that require concentration -- especially when first starting trimipramine or when switching dosages. This is because trimipramine may affect a person's mental or physical ability to perform these tasks. Make sure to understand how trimipramine affects you before performing any task that requires mental or physical concentration.
- Trimipramine can interact with certain other medications (see Drug Interactions With Trimipramine).
- Trimipramine may not be safe for use during pregnancy. Talk with your healthcare provider about the benefits and risks of using trimipramine during pregnancy (see Surmontil and Pregnancy for more information).
- It is not known if trimipramine passes through breast milk. Therefore, if you are breastfeeding or plan to start breastfeeding, be sure to talk with your healthcare provider about what makes the most sense for your particular situation (see Surmontil and Breastfeeding).
- Special care should be used when taking trimipramine if you have a history of seizures, bladder problems, or glaucoma. Trimipramine can make these conditions worse.
- Talk with your healthcare provider before taking trimipramine if you have any heart problems, as the drug can affect the heart and its electrical system.
- Talk with your healthcare provider before taking trimipramine if you have hyperthyroidism (overactive thyroid) or take thyroid medication.
- Taking trimipramine while receiving electroshock or electroconvulsive therapy (ECT) can increase your risk of side effects. Talk with your healthcare provider about these risks.
- Trimipramine may cause a dry mouth. Sucking on hard candy, chewing gum, or melting bits of ice in your mouth can provide relief.
- Elderly people appear to be more sensitive to trimipramine, which can increase their risk of side effects (such as delirium and confusion). In these particular situations, the healthcare provider will start people on lower doses of trimipramine and monitor them more closely.
- If you have diabetes, make sure to check your blood sugar levels more often than usual when starting trimipramine or changing dosages. There have been reports of increased or decreased blood sugar levels in people who take trimipramine.
- Do not treat yourself for the common cold, a cough, or allergies without first talking with your healthcare provider. Some of these medicines can increase the risk of developing trimipramine side effects.
- Do not stop taking trimipramine without first discussing it with your healthcare provider. Stopping the medicine abruptly may increase the risk of withdrawal symptoms (see Surmontil Withdrawal).