Depression
Medications
Related eMedTV
Health Channels

Trimipramine

Trimipramine is a medication that is used for the treatment of depression in adults. It is a type of tricyclic antidepressant that works by affecting certain chemicals in the brain (serotonin and norepinephrine). Some possible side effects of trimipramine include dizziness or lightheadedness, a dry mouth, and constipation. Trimipramine capsules, which are available by prescription, come in three different strengths and are generally taken one to four times a day.

 

What Is Trimipramine?

Trimipramine maleate (Surmontil®) is a prescription medication that is used to treat depression (also known as major depression or clinical depression).
 
(Click What Is Trimipramine Used For? for more information on trimipramine uses, including possible off-label uses.)
 

Who Makes Trimipramine?

Trimipramine is made by Duramed Pharmaceuticals.
 

How Does Trimipramine Work?

Trimipramine belongs to a class of medications called tricyclic antidepressants. It is not entirely clear how trimipramine works. However, it is known that trimipramine affects several chemicals in the brain, including serotonin and norepinephrine. It is thought that perhaps trimipramine allows these chemicals to stay in the brain longer, which can help with depression symptoms.
 

When and How to Take Trimipramine

Some considerations for when and how to take trimipramine include:
 
  • Trimipramine comes in capsule form. When used for depression, it is usually taken by mouth one to four times daily.
     
  • It does not matter if you take trimipramine with or without food. If it upsets your stomach, try taking it with food.
     
  • Trimipramine should be taken at the same times each day to maintain even levels of the medication in your blood.
     
  • For the antidepressant to work properly, you have to take it as prescribed. Trimipramine will not work if you stop taking it.
     
(Trimipramine Continued: Page 2)
Add this article to your Favorites     Email this article     Print
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;