Interactions With Venlafaxine XR Explained
The following sections explain in detail the potentially negative interactions that can occur when
venlafaxine XR is combined with any of the drugs listed above.
Alcohol
It is not recommended that you drink alcohol while taking
venlafaxine XR. Combining alcohol and venlafaxine XR may cause unwanted side effects
(see Alcohol and Effexor XR).
"Blood Thinners"
Combining venlafaxine XR with anticoagulant or antiplatelet medications (commonly known as blood thinners) may increase the risk of bleeding. Check with your healthcare provider before taking such medications with venlafaxine XR.
Cimetidine (Tagamet)
Taking
cimetidine and venlafaxine XR together can increase the level of venlafaxine XR in your blood, increasing your risk of side effects. Your healthcare provider may need to lower your venlafaxine XR dose or may suggest an alternative to cimetidine. However, this interaction is usually not a problem (except for people with
high blood pressure or liver problems).
Haloperidol (Haldol)
Taking venlafaxine XR with
haloperidol can raise the level of haloperidol in your blood, increasing your risk of side effects. If you are taking these drugs together, your healthcare provider may need to decrease your haloperidol dosage.
Indinavir (Crixivan)
Taking venlafaxine XR with
indinavir may decrease the level of indinavir in your blood, perhaps making it less effective. If you are taking these drugs together, your healthcare provider may need to increase your dose of indinavir.
Ketoconazole (Nizoral)
Taking venlafaxine XR with ketoconazole may raise the level of venlafaxine XR in your blood, increasing your risk of side effects. If you are taking these drugs together, your healthcare provider may need to decrease your venlafaxine XR dosage.
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