Side Effects of Venlafaxine XR

Venlafaxine Sustained Release

Side Effects of Venlafaxine XR to Report

There are a number of less common but more serious side effects of venlafaxine XR that you should report to your healthcare provider. These include (but are not limited to):

Suicidal thoughts or behavior (see Effexor XR and Suicide)
Anxiety, agitation, or panic attacks
Hostility or aggressiveness
Engaging in unusual or dangerous activities
Restlessness or inability to sit still
Extreme elation, or a feeling of happiness that may switch back and forth with a depressed or sad mood
Other unusual changes in behavior
Signs of serotonin syndrome (a rare but dangerous problem associated with certain medications) such as:
- Confusion or other mental changes
- A rapid heart rate
- Nausea, vomiting, or diarrhea
- Hallucinations
- Blood pressure changes
- An irregular heart rhythm
- Overactive reflexes
- Fever, sweating, or shivering
- Shakiness
- Agitation
- Seizures
- Coma

Heart palpitations
Difficulty sleeping
Difficulty breathing, coughing, or chest pain
Signs of an allergic reaction, including unexplained rash, hives, itching, unexplained swelling, wheezing, or difficulty breathing or swallowing.

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