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Wellbutrin XL Drug Interactions

Nelfinavir
Nelfinavir may interact with Wellbutrin XL, although there have been no reports of such an interaction in actual patients. Your healthcare provider may need to monitor you more closely and may need to adjust your dose of these medications.
 
Nicotine Patches
Taking Wellbutrin XL while using nicotine patches can cause high blood pressure (hypertension). Your healthcare provider should monitor your blood pressure if you are taking these medications together.
 
Orphenadrine
Orphenadrine may interact with Wellbutrin XL, although there have been no reports of such an interaction in actual patients. Your healthcare provider may need to monitor you more closely and may need to adjust your dose of these medications.
 
Ritonavir
Ritonavir may interact with Wellbutrin XL, although there have been no reports of such an interaction in actual patients. Your healthcare provider may need to monitor you more closely and may need to adjust your dose of these medications.
 
Steroids
Combining Wellbutrin XL with intravenous or oral steroids can increase your risk of seizures. Talk to your healthcare provider before taking these medications together.
 
Theophylline
Taking Wellbutrin XL and theophylline together can increase your risk of seizures. Talk to your healthcare provider before taking Wellbutrin XL and theophylline together.
 
Thiotepa
Thiotepa may interact with Wellbutrin XL, although there have been no reports of such an interaction in actual patients. Your healthcare provider may need to monitor you more closely and may need to adjust your dose of these medications.
 
(Wellbutrin XL Drug Interactions Continued: Page 5)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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