Some side effects with Wellbutrin XL, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
Extreme elation or feelings of happiness that may switch back and forth with a depressed or sad mood
Other unusual changes in behavior
Hallucinations
A fast heart rate
Chest palpitations
Difficulty sleeping
Feelings of internal jitteriness or restlessness
Signs of an allergic reaction, such as:
An unexplained rash
Hives
Itching
Unexplained swelling
Wheezing
Difficulty breathing or swallowing.
Rare Wellbutrin XL Side Effects
Rare side effects of Wellbutrin XL occur in less than 1 percent of people taking the drug. Because these side effects are so uncommon, it is difficult to tell whether they are because of the medication or something else. Wellbutrin SR® (a similar medication) has been studied in more people (and has been available longer than Wellbutrin XL); therefore, most of the information about rare side effects comes from studies of Wellbutrin SR.
In the studies on Wellbutrin SR, some of these rare side effects include but are not limited to: