Beta Blockers
Wellbutrin may raise the level of
beta blockers in your blood, increasing your risk of side effects. If you are taking these drugs together, your healthcare provider may need to monitor you more closely and may need to decrease your dose of beta blockers.
Certain Arrhythmia Medications
Wellbutrin may increase the levels of certain arrhythmia medications in your blood, increasing your risk of side effects. If you are taking these drugs together, your healthcare provider may need to monitor you more closely, especially when you are starting or stopping Wellbutrin.
Clopidogrel
Clopidogrel may slow the metabolism of Wellbutrin in the body, potentially leading to high levels of this medication, and a potentially higher risk of
Wellbutrin side effects. Check with your healthcare provider before taking these medications together.
Cyclophosphamide (Cytoxan)
While it is thought that
cyclophosphamide may interact with Wellbutrin, there have been no reports of such an interaction in actual patients. If you are taking cyclophosphamide and Wellbutrin together, your healthcare provider may need to monitor you more closely and may need to adjust your doses of these medications.
Doxorubicin (Adriamycin, Doxil)
Doxorubicin may raise the level of Wellbutrin in your blood, increasing your chance of side effects. Your healthcare provider may need to decrease your Wellbutrin dose while you are taking doxorubicin.
Efavirenz (Sustiva)
Efavirenz may increase the metabolism of Wellbutrin, leading to decreased levels of Wellbutrin in the blood, and possibly to decreased effectiveness. Check with your healthcare provider before taking such medications together. You may need a higher
Wellbutrin dosage, although the maximum recommended dosage should not be exceeded, even if you are taking efavirenz.
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