A few common side effects of Wellbutrin^® (bupropion hydrochloride) include appetite loss, blurred vision, agitation, and insomnia. Rare side effects of this medicine can include mood swings, memory loss, and flushing. There are also a number of Wellbutrin side effects that you should report to your healthcare provider, including seizures, hallucinations, difficulty sleeping, and suicidal thoughts or behavior. You should also let your healthcare provider know if you experience anything that "just does not seem right" while taking this medication.