Alcohol and Zoloft
Drinking alcohol while taking Zoloft does not seem to increase the impairment of mental and motor skills that alcohol causes in normal subjects. However, the effects of alcohol and Zoloft on people with depression, OCD, panic disorder, PTSD, PMDD, and/or social anxiety disorder have not been studied. This is one reason for using caution with Zoloft and alcohol.
If a person decides to drink alcohol in moderation while on Zoloft, he or she should use caution. For example, people should not consume alcohol at the same time they take a dose of Zoloft. Also, people should learn how Zoloft affects them before drinking alcohol. Zoloft may affect some individuals' ability to perform certain functions, such as driving a car or operating machinery.
You should talk with your healthcare provider about Zoloft and alcohol. Everyone's situation is different, and your healthcare provider understands your situation best. Based what you want and expect, and your current health situation, you and your healthcare provider can make a shared decision that's best for you.