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Negative Effects of Zoloft

Although most people tolerate
 Zoloft® (sertraline hydrochloride) well, it is not free of negative effects. Because this medication is not suitable for everyone, talk to your healthcare provider about any possible problems that may apply to you. For instance, make sure your healthcare provider is aware of other medical conditions you have and other medications you are taking (including non-prescription medications, vitamins, and herbal supplements) before starting treatment with Zoloft. Negative effects of this medication include potential side effects. Commonly reported ones include:
 
  • Nausea
  • Insomnia
  • Ejaculation problems
  • Diarrhea or loose stools
  • Dizziness
  • Dry mouth.
 
Although negative effects of Zoloft tend to be minor and either require no treatment or are easily treated, there are some serious side effects that require medical attention. Contact your healthcare provider right away if you experience hallucinations, suicidal thoughts, or a fast heart rate.
 
(Click Zoloft Side Effects and Zoloft Warnings and Precautions for more information on potentially negative effects of Zoloft to be aware of before starting treatment. These articles also explain what to tell your healthcare provider before using Zoloft and who may not be able to safely use it.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;