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Problems With Zoloft

 Zoloft® (sertraline hydrochloride) is a prescription medicine licensed to treat conditions within the brain, such as depression, obsessive-compulsive disorder, and premenstrual dysphoric disorder.
 
Most people tolerate this medication well, but it is possible to develop problems with Zoloft. Some of the most common side effects that have been reported with adults using this drug include indigestion, nausea, and fatigue. In children, common side effects included bloody nose, fever, and urinary incontinence (loss of bladder control).
 
In most cases, side effects are mild and either do not require medical attention or can be treated easily. However, certain Zoloft problems are potentially serious and should be reported to your healthcare provider right away, including anxiety, difficulty breathing, or fast heart rate.
 
(Click Zoloft Side Effects to learn about other possible problems with Zoloft, including other potentially serious side effects that require prompt medical attention.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;