Zoloft^® (sertraline hydrochloride) is a medication that is licensed to treat depression, premenstrual dysphoric disorder (PMDD), panic disorder, and post-traumatic stress disorder (PTSD). It is also licensed to treat obsessive-compulsive disorder (OCD) and social anxiety disorder. Zoloft is part of a class of drugs referred to as selective serotonin reuptake inhibitors (SSRIs). The drug comes in tablet form; it is also available as a liquid. Generally, you take it once a day.

(Click Zoloft for more detailed information about this prescription medication, including a discussion of how this drug and other SSRIs work, and guidelines for how and when to best take the medication.)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD

Last reviewed by: Kristi Monson, PharmD

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