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Zoloft Dosage

The Zoloft dosage that doctors usually recommend for adults with depression or obsessive-compulsive disorder (OCD) is 50 mg once a day. Although the starting dose of Zoloft for people with panic disorder, post-traumatic stress disorder (PTSD), or social anxiety disorder is typically 25 mg daily, healthcare providers often increase that dose to 50 mg daily after about a week. The recommended Zoloft dosage for children with OCD is usually 25 mg daily.

 

Zoloft Dosage: An Introduction

The dose of Zoloft® (sertraline hydrochloride) your healthcare provider prescribes will vary depending on a number of factors, including:
 
  • Your age
  • The medical condition for which you are being treated
  • Other medical conditions you may have
  • Other medications you may be taking.
     
As is always the case, do not adjust your Zoloft dose unless your healthcare provider specifically instructs you to do so.
 

Zoloft Dosing for Depression or Obsessive-Compulsive Disorder (OCD)

The recommended starting Zoloft dose for people with depression or obsessive-compulsive disorder (OCD) is Zoloft 50 mg once a day. The healthcare provider may choose to increase the Zoloft dosage if symptoms continue, or decrease the dose if side effects occur.
 

Zoloft Dosing for Panic Disorder, Post-Traumatic Stress Disorder, or Social Anxiety Disorder

The recommended starting Zoloft dose for people with panic disorder, post-traumatic stress disorder (PTSD), or social anxiety disorder is Zoloft 25 mg once a day. After a week, the healthcare provider will likely increase the dose up to 50 mg of Zoloft once a day. The healthcare provider may choose to increase the Zoloft dosage if symptoms continue, or decrease the dose if side effects occur.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;