Zoloft Drug Interactions

Tolbutamide
Taking Zoloft with tolbutamide may increase the level of tolbutamide in your blood, possibly increasing your risk of side effects (including low blood sugar). Your healthcare provider may need to decrease your tolbutamide dosage to prevent interactions from occurring.
 
Tramadol (Rybix ODT, Ryzolt, Ultram, Ultram ER) or Tramadol and Acetaminophen (Ultracet)
Combining Zoloft with tramadol can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome, as it can be dangerous.
 
Tricyclic Antidepressants
Taking Zoloft with tricyclic antidepressants can increase the level of tricyclic antidepressants in your blood. Your healthcare provider may need to reduce your dose of the tricyclic medication to prevent interactions from occurring.
 
Triptans
Taking Zoloft with a triptan can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together and call your healthcare provider right away if you have any possible symptoms, as the condition can be dangerous.
 
Tryptophan
Combining Zoloft and tryptophan can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together and call your healthcare provider right away if you have any symptoms, as it can be dangerous.
 
Warfarin
Taking Zoloft and warfarin together may increase your risk of bleeding. Your healthcare provider may choose to monitor you more closely when you are starting or stopping Zoloft.
 
Feed Your Adult ADHD Brain

Zoloft Medication

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