The most common side effects of Zoloft® (sertraline hydrochloride) include such things as nausea, insomnia, and diarrhea. Indigestion, dry mouth, dizziness, and fatigue are examples of other relatively common side effects seen with Zoloft. Side effects of Zoloft that are less common but more serious can include such things as suicidal thoughts or behavior, fast heart rate, and panic attacks.
(Click Zoloft Side Effects for a more detailed discussion of side effects reported with Zoloft, including information about other rare but serious health problems the drug may cause.)