Medications
 
 

Zoloft Side Effects

Common Side Effects in Children

Side effects in children taking Zoloft are generally similar to those seen in adults taking the medication. However, some common side effects of Zoloft that appear to occur more often in children include:
 
  • Fever
  • Hyperactivity
  • Urinary incontinence (loss of bladder control)
  • Aggressiveness
  • Sinus infection or inflammation
  • Bloody nose
  • Red or purple discolorations on the skin (purpura).
     

Side Effects to Report

Some side effects of Zoloft, while occurring infrequently, are potentially serious and should be reported to your healthcare provider. These include but are not limited to:
 
  • Suicidal thoughts or behavior (see Zoloft and Suicide)
  • Anxiety, agitation, or panic attacks
  • Hostility or aggressiveness
  • Engaging in unusual or dangerous activities
  • Extreme elation or feeling of happiness that may switch back and forth with a depressed or sad mood
  • Other unusual changes in behavior
  • Signs of serotonin syndrome (a rare but dangerous problem associated with certain medications), such as:
  •  
    • Confusion or other mental changes
    • A rapid heart rate
    • Nausea, vomiting, or diarrhea
    • Hallucinations
    • Blood pressure changes
    • An irregular heart rhythm
    • Overactive reflexes
    • Fever, sweating, or shivering
    • Shakiness
    • Agitation
    • Seizures
    • Coma

 

  • Chest palpitations
  • Feelings of internal restlessness or jitteriness
  • Signs of an allergic reaction, such as:
 
    • Unexplained rash
    • Hives
    • Itching
    • Unexplained swelling
    • Wheezing
    • Difficulty breathing or swallowing.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
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