Depression Home > Desipramine

Desipramine is a type of tricyclic antidepressant that is licensed to treat depression in adults. By affecting certain chemicals in the brain (serotonin and norepinephrine), the medication can help reduce depression symptoms. Desipramine comes in tablet form and is available in a number of strengths. The drug is generally taken one to four times a day. Side effects may include drowsiness, dizziness, and confusion.

What Is Desipramine?

Desipramine hydrochloride (Norpramin®) is a prescription medication that is used to treat depression (also known as major depression or clinical depression).
(Click What Is Desipramine Used For? for more information on the drug's uses, including possible off-label uses.)

Side Effects

As with any medicine, there are possible side effects with desipramine. However, not everyone who takes the medication will experience side effects. In fact, most people tolerate it well. When desipramine side effects do occur, they are often minor and either require no treatment or can easily be treated by your healthcare provider. Serious side effects of desipramine are less common.
Some common side effects of tricyclic antidepressants (such as desipramine) include:
(Click Desipramine Side Effects to learn about specific side effects of the medication, including some of the more serious side effects that you should report to your healthcare provider.)
You can also read about other possible side effects by clicking on the following links:
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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