Depression Home > Isocarboxazid

Isocarboxazid, a prescription medication that belongs to a class of drugs known as monoamine oxidase inhibitors (MAOIs), is approved to treat depression. The medication has many potentially lethal drug and food interactions and is often used as a last resort when other antidepressants have failed. This drug comes in the form of a tablet that is taken by mouth, usually two to four times a day.

What Is Isocarboxazid?

Isocarboxazid (Marplan®) is a prescription medication that is used to treat depression (also known as major depression or clinical depression). Because this medication has several potentially lethal drug and food interactions, it is often used as a last resort, when other antidepressants have failed.
(Click What Is Isocarboxazid Used For? for more information on what this drug is used for, including possible off-label uses.)

Are There Side Effects?

As with any medicine, there are possible side effects with isocarboxazid. However, not everyone who takes it will experience side effects. In fact, most people tolerate the medication well. When side effects do occur, they are often minor and either require no treatment or can easily be treated by you or your healthcare provider. Serious side effects are less common.
Some of the side effects of isocarboxazid include:
(Click Side Effects of Isocarboxazid to learn about specific side effects of isocarboxazid, including some of the more serious side effects that you should report to your healthcare provider. You can also read about other possible side effects by going to:
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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