Depression Home > Ludiomil

Ludiomil is a prescription medicine licensed for the treatment of depression and anxiety associated with depression. The medication helps to improve symptoms by allowing certain chemicals to stay in the brain longer. It is available in three different strengths, comes in tablet form, and is generally taken one to four times a day. Potential side effects include drowsiness, nervousness, and dry mouth.

What Is Ludiomil?

Ludiomil® (maprotiline hydrochloride) is a prescription medication that is used to treat depression (also known as major depression or clinical depression). It is also approved to treat anxiety associated with depression.
(Click Ludiomil Uses for more information, including possible off-label uses.)

Who Makes Ludiomil?

Ludiomil is no longer available. Generic Ludiomil is still available and is made by Mylan Pharmaceuticals.

How Does This Medication Work?

Although Ludiomil is technically a tetracyclic antidepressant due to its chemical structure, most sources consider it to be a tricyclic antidepressant because it is so similar to other tricyclic antidepressants.
It is not entirely clear how Ludiomil works. The medication does affect several chemicals in the brain, including serotonin and norepinephrine. It is thought that perhaps Ludiomil allows these chemicals to stay in the brain longer, which can help with depression symptoms.

When and How to Take Ludiomil

Some considerations to keep in mind during treatment with Ludiomil include the following:
  • Ludiomil comes in tablet form. It is usually taken by mouth one to four times daily.
  • You can take this medicine with or without food. If Ludiomil upsets your stomach, try taking it with food.
  • Ludiomil should be taken at the same time(s) each day to maintain an even level in your blood.
  • For Ludiomil to work properly, you have to take it as prescribed. The medication will not work if you stop taking it.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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