Depression Home > Trimipramine Dosing

For adults who are beginning depression treatment with trimipramine, dosing usually starts at 75 mg per day (taken in two or three smaller doses throughout the day). If you tolerate the medication well, your healthcare provider may increase your daily dose up to 200 mg. The recommended trimipramine dosage for elderly people or teenagers is 50 mg daily. To maintain an even level of medicine in your blood, be sure to take your doses at the same times each day.

An Overview of Trimipramine Dosing

The dose of trimipramine maleate (Surmontil®) that your healthcare provider prescribes will vary depending on a number of factors, including:
  • Your age
  • Other medical conditions you may have
  • Other medications you may be currently taking.
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.

Trimipramine Dosing for Depression

The recommended starting trimipramine dose for depression is 75 mg total per day, divided into two or three smaller doses per day. Your healthcare provider may increase your dose (if necessary) if you tolerate trimipramine well, up to a maximum of 200 mg total per day (or 300 mg in certain rare circumstances). Also, your healthcare provider may recommend taking your entire daily dose all at once at bedtime, instead of taking several smaller doses per day.
Although trimipramine is not approved for use in teens, the manufacturer gives recommendations for trimipramine dosing in teens. For teenage depression or depression in the elderly, lower doses are recommended. The recommended starting dose for teens or elderly people is trimipramine 50 mg total per day. The maximum dose for these age groups is trimipramine 100 mg per day.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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