Pristiq Side Effects

Dry mouth, dizziness, and nausea are the most common side effects reported with Pristiq. Side effects that are less common (occurring in less than 2 percent of people) include hot flashes, nosebleeds, and yawning. Most side effects are minor and easily treated. However, contact your healthcare provider immediately if you experience such side effects of Pristiq as hallucinations, seizures, or panic attacks.

An Introduction to Pristiq Side Effects

As with any medicine, side effects are possible with Pristiq® (desvenlafaxine succinate); however, not everyone who takes the drug will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Pristiq. Your healthcare provider can discuss a more complete list of Pristiq side effects with you.)

Common Side Effects of Pristiq

Pristiq has been studied thoroughly in clinical trials. In these trials, one group of people was given the medication, while another group was given a placebo (a "sugar pill" with no active ingredients). This way, it is possible to see what side effects occurred, how often they appeared, and how they compared to the group who took the placebo.
In these studies, the most common side effects of Pristiq (when taken at the recommended dose of 50 mg per day) included:
  • Nausea -- in up to 22 percent of people
  • Dizziness -- up to 13 percent
  • Dry mouth -- up to 11 percent
  • Diarrhea -- up to 11 percent
  • Increased sweating -- up to 10 percent.
Other common side effects (occurring in 2 to 9 percent of people) include but are not limited to:
  • Constipation
  • Fatigue
  • Decreased appetite
  • Weight loss
  • Insomnia
  • Irritability
  • Abnormal dreams
  • Blurred vision
  • Ringing in the ears (tinnitus)
  • A spinning sensation (vertigo) 
  • Decreased sex drive (libido) in men
  • Impotence (also known as erectile dysfunction or ED).
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Pristiq Drug Information

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